About Pyle disease
Pyle disease is a rare disease catalogued by Orphanet (ORPHA:3005). It is associated with the SFRP4 gene. Search below for active recruiting clinical trials from ClinicalTrials.gov, or visit the Orphanet expert page for specialist centres, natural history studies, and patient registries.
Clinical Trial Eligibility Tips
What to know before applying to Pyle disease trials.
Search ClinicalTrials.gov for "Pyle disease" or filter by Orphanet code ORPHA:3005 to find disease-specific studies.
Ask your specialist to refer you to a Centre of Expertise — Orphanet lists all accredited centres for this condition worldwide.
Natural history studies and patient registries often enrol before drug trials open — contact the Orphanet patient community first.
Patient Resources
Find recruiting Pyle disease trials
Search 500,000+ studies from ClinicalTrials.gov, filtered for Pyle disease. Updated daily.