Rare condition

Pure autonomic failure

11

studies recruiting now

as of 7 Sept 2026

70

studies registered in total

as of 7 Sept 2026

6

countries with a recruiting site

as of 7 Sept 2026

9 Apr 2025

most recent study posted

among recruiting studies

Recruiting trials

Showing the 5 most recently updated recruiting studies, as recorded 7 Sept 2026. Live status on each study page.

See all 11 recruiting studies

Where recruiting studies are running

Countries with at least one recruiting site among the studies above, 7 Sept 2026. Tap a country to search trials there.

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Patient organisations

We do not yet list a dedicated organisation for this condition. The directories below are the best route.

About Pure autonomic failure

RareTrial does not yet hold a plain-language description of this condition. The most reliable starting point is Orphanet’s expert page, which lists specialist centres, registries and patient organisations.

Treatments being studied

2 approved treatments and 18 in clinical development, from Open Targets (CC BY 4.0). Not medical advice.

Approved: Droxidopa (Northera)Approved: Ioflupane I 123 (Celsunax)
Phase 3Riluzole (Exservan)
Phase 3Rifampin (Eremfat)
Phase 3Verdiperstat
Phase 3Amlenetug
Phase 3Epigalocatechin Gallate
Phase 2Inosine
Phase 2Lithium Carbonate (Camcolit 250)
Phase 2Foralumab

+ 10 more in development

Related conditions

Information, not medical advice. Trial listings are shown as recorded on ClinicalTrials.gov; whether any study is right for you is a decision for you and your clinicians, and eligibility is decided by each research team. Disease information from Orphanet (CC BY 4.0).