RecruitingPhase 3NCT07220772
Rare condition
Obesity due to leptin receptor gene deficiency
1
studies recruiting now
as of 7 Sept 2026
2
studies registered in total
as of 7 Sept 2026
1
countries with a recruiting site
as of 7 Sept 2026
24 Oct 2025
most recent study posted
among recruiting studies
Recruiting trials
Showing the 1 most recently updated recruiting study, as recorded 7 Sept 2026. Live status on each study page.
Search all Obesity due to leptin receptor gene deficiency studiesWhere recruiting studies are running
Countries with at least one recruiting site among the studies above, 7 Sept 2026. Tap a country to search trials there.
Keep watching
Get an email when a new Obesity due to leptin receptor gene deficiency study opens.
One email a day at most. Unsubscribe with one click.
Used only for these alerts. Privacy.
Support
Patient organisations
We do not yet list a dedicated organisation for this condition. The directories below are the best route.
About Obesity due to leptin receptor gene deficiency
RareTrial does not yet hold a plain-language description of this condition. The most reliable starting point is Orphanet’s expert page, which lists specialist centres, registries and patient organisations, and the gene involved (LEPR).
Treatments being studied
34 approved treatments and 194 in clinical development, from Open Targets (CC BY 4.0). Not medical advice.
Approved: Diethylpropion Hydrochloride (Apisate)Approved: QuercetinApproved: Sibutramine (Reductil)Approved: MefenorexApproved: Choriogonadotropin Alfa (Ovidrel)Approved: Naltrexone (Celupan)Approved: DexfenfluramineApproved: DiethylpropionApproved: Setmelanotide Acetate (Imcivree)Approved: Amphetamine Sulfate (Amphetamine sulfate)Approved: Orlistat (Alli)Approved: FenfluramineApproved: CathineApproved: Phentermine (Duromine)Approved: EtilamfetamineApproved: Rimonabant (Acomplia)Approved: Liraglutide (Liraglutide component of xultophy 100/3.6)Approved: PhenylpropanolamineApproved: Phendimetrazine Tartrate (Adphen)Approved: BupropionApproved: Benzphetamine Hydrochloride (Benzphetamine hydrochloride)Approved: Mazindol (Mazanor)Approved: Propylhexedrine (Dristan inhaler)Approved: PhendimetrazineApproved: Phentermine Hydrochloride (Adipex-p)Approved: LorcaserinApproved: Semaglutide (Ozempic)Approved: CetilistatApproved: ClobenzorexApproved: BenzphetamineApproved: Tirzepatide (Mounjaro)Approved: Setmelanotide (Imcivree)Approved: PhenmetrazineApproved: Ephedrine
Phase 3Metreleptin (Myalepta)
Phase 3Retatrutide
Phase 3Leuprolide Acetate (Eligard)
Phase 3Propofol (Diprivan)
Phase 3Otenabant
Phase 3Sodium Deoxycholate
Phase 3Mazdutide
Phase 3Rosuvastatin
+ 186 more in development
Related conditions
Information, not medical advice. Trial listings are shown as recorded on ClinicalTrials.gov; whether any study is right for you is a decision for you and your clinicians, and eligibility is decided by each research team. Disease information from Orphanet (CC BY 4.0).