Rare condition

Down syndrome

ORPHA:870 ↗Malformation syndrome

81

studies recruiting now

as of 7 Sept 2026

483

studies registered in total

as of 7 Sept 2026

6

countries with a recruiting site

as of 7 Sept 2026

25 Aug 2026

most recent study posted

among recruiting studies

Recruiting trials

Showing the 5 most recently updated recruiting studies, as recorded 7 Sept 2026. Live status on each study page.

See all 81 recruiting studies

Where recruiting studies are running

Countries with at least one recruiting site among the studies above, 7 Sept 2026. Tap a country to search trials there.

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Patient organisations

We do not yet list a dedicated organisation for this condition. The directories below are the best route.

About Down syndrome

RareTrial does not yet hold a plain-language description of this condition. The most reliable starting point is Orphanet’s expert page, which lists specialist centres, registries and patient organisations.

Treatments being studied

15 in clinical development, from Open Targets (CC BY 4.0). Not medical advice.

Phase 3Leucovorin Calcium (Leucovorin calcium)
Phase 3Leucovorin
Phase 3Thyroid (Nature)
Phase 3Donepezil Hydrochloride (Adlarity)
Phase 3Dextrothyroxine
Phase 2Basmisanil
Phase 2Bumetanide (Betinex)
Phase 2Scyllitol

+ 7 more in development

Information, not medical advice. Trial listings are shown as recorded on ClinicalTrials.gov; whether any study is right for you is a decision for you and your clinicians, and eligibility is decided by each research team. Disease information from Orphanet (CC BY 4.0).