Immune

Langerhans cell histiocytosis

58

studies recruiting now

as of 7 Sept 2026

269

studies registered in total

as of 7 Sept 2026

4

countries with a recruiting site

as of 7 Sept 2026

2 Sept 2026

most recent study posted

among recruiting studies

Recruiting trials

Showing the 5 most recently updated recruiting studies, as recorded 7 Sept 2026. Live status on each study page.

See all 58 recruiting studies

Where recruiting studies are running

Countries with at least one recruiting site among the studies above, 7 Sept 2026. Tap a country to search trials there.

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Patient organisations

We do not yet list a dedicated organisation for this condition. The directories below are the best route.

About Langerhans cell histiocytosis

RareTrial does not yet hold a plain-language description of this condition. The most reliable starting point is Orphanet’s expert page, which lists specialist centres, registries and patient organisations, and the genes involved (MAP2K1, NRAS, BRAF).

Treatments being studied

13 in clinical development, from Open Targets (CC BY 4.0). Not medical advice.

Phase 3Prednisone (Cortan)
Phase 3Vinblastine
Phase 3Cytarabine (Alexan)
Phase 2Afuresertib
Phase 2Clofarabine (Clolar)
Phase 2Trametinib (Mekinist)
Phase 2Thalidomide (Kevadon)
Phase 2Thioguanine (Lanvis)

+ 5 more in development

Related conditions

Information, not medical advice. Trial listings are shown as recorded on ClinicalTrials.gov; whether any study is right for you is a decision for you and your clinicians, and eligibility is decided by each research team. Disease information from Orphanet (CC BY 4.0).