Disease Directory Langerhans cell histiocytosis
Immune

Langerhans cell histiocytosis

Type

Disease

Gene

MAP2K1, NRAS, BRAF

About Langerhans cell histiocytosis

Langerhans cell histiocytosis is a rare disease catalogued by Orphanet (ORPHA:389). It is associated with the MAP2K1, NRAS, BRAF genes. Search below for active recruiting clinical trials from ClinicalTrials.gov, or visit the Orphanet expert page for specialist centres, natural history studies, and patient registries.

Clinical Trial Eligibility Tips

What to know before applying to Langerhans cell histiocytosis trials.

Search ClinicalTrials.gov for "Langerhans cell histiocytosis" or filter by Orphanet code ORPHA:389 to find disease-specific studies.

Ask your specialist to refer you to a Centre of Expertise — Orphanet lists all accredited centres for this condition worldwide.

Natural history studies and patient registries often enrol before drug trials open — contact the Orphanet patient community first.

Patient Resources

Patient Organization

Orphanet

Visit website ↗

Orphanet

European reference resource for rare diseases (ORPHA:389)

View on Orphanet ↗

NORD

National Organization for Rare Disorders

Search NORD ↗

Find recruiting Langerhans cell histiocytosis trials

Search 500,000+ studies from ClinicalTrials.gov, filtered for Langerhans cell histiocytosis. Updated daily.