Disease Directory Cleft lip and alveolus
Rare Disease

Cleft lip and alveolus

Type

Morphological anomaly

Gene

MSX1, TP63, IRF6, NECTIN1

About Cleft lip and alveolus

Cleft lip and alveolus is a rare disease catalogued by Orphanet (ORPHA:141291). It is associated with the MSX1, TP63, IRF6 genes. Search below for active recruiting clinical trials from ClinicalTrials.gov, or visit the Orphanet expert page for specialist centres, natural history studies, and patient registries.

Clinical Trial Eligibility Tips

What to know before applying to Cleft lip and alveolus trials.

Search ClinicalTrials.gov for "Cleft lip and alveolus" or filter by Orphanet code ORPHA:141291 to find disease-specific studies.

Ask your specialist to refer you to a Centre of Expertise — Orphanet lists all accredited centres for this condition worldwide.

Natural history studies and patient registries often enrol before drug trials open — contact the Orphanet patient community first.

Patient Resources

Patient Organization

Orphanet

Visit website ↗

Orphanet

European reference resource for rare diseases (ORPHA:141291)

View on Orphanet ↗

NORD

National Organization for Rare Disorders

Search NORD ↗

Find recruiting Cleft lip and alveolus trials

Search 500,000+ studies from ClinicalTrials.gov, filtered for Cleft lip and alveolus. Updated daily.